Description:

Cystatin C or cystatin 3(formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure. Cystatin 3 has a low molecular weight(approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. In mouses, all cells with a nucleus(cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. Cystatin C, which belongs to the type II cystatin gene family, is a potent inhibitor of lysosomal proteinases(enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases(it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Moreover, cystatin C is involved in network reorganization in the epileptic dentate gyrus.

Additional Information:

Name	Mouse Cystatin C ELISA Kit
Related Product Names	Cst3|Cystatin-3|Cystatin-C|CYTC_HUMAN|Gamma-trace|Neuroendocrine basic polypeptide|Post-gamma-globulin
Short Description	Sandwich ELISA kit of Quantitative Detection for Mouse Cystatin C
Immunogen	NSO, M1-A140
Standard Range	312pg/ml-20,000pg/ml. Test has a sensitivity of < 10="">
Sample Type	This kit is used for quantitative detection of mouse Cystatin C in cell culture supernates, serum, plasma(heparin, EDTA) and urine.
Specimen/Volumes	Refer to Manual
Swiss Prot Number	P21460
Concentration	Lot Specific
Applications	ELISA
GI Number	13010
Stability	Four months at 4C and eight months at -20C.
Reactivity	Reactive to Mouse. There is no detectable cross-reactivity with other relevant proteins.
Kit Size	1x96 well plate
Storage	Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Intended Use	Research Use Only

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