Description:
Theprotein,alsocalledPGF,is149aminoacidslongandshares53%identitywiththeplatelet-derivedgrowthfactor-likeregionofhumanVPF.AndtheN-glycosylatedPLGFproteinissecretedintothemediumandthatitfunctionsasadimer1.ThePLGFgeneismappedto14q24-q31.Thereare3isoformsofPGF,designatedPGF1,PGF2,andPGF3.OnlyPGF2isabletobindheparin.Additionally,PGFregulatesinter-andintramolecularcross-talkbetweentheVEGFreceptortyrosinekinasesFLT1andFLK12.ItalsocanstimulateangiogenesisandcollateralgrowthinischemicheartandlimbwithatleastacomparableefficiencytoVEGF3.
AdditionalInformation:
Name | HumanPLGFELISAKit |
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RelatedProductNames | AI854365|D12S1900|MGC93298|Pgf|PGFL|PIGF|Placentagrowthfactor|Placentalgrowthfactor|Placentalgrowthfactorvascularendothelialgrowthfactorrelatedprotein|PlGF|PlGF2|PLGF_HUMAN|PlGF2|SHGC10760|Vascularendothelialgrowthfactorr |
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ShortDescription | SandwichELISAkitofQuantitativeDetectionforHumanPlacentalGrowthFactor |
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Immunogen | E.coli,A21-R149 |
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StandardRange | 15.6pg/ml-1000pg/ml.Testhasasensitivityof<1=""> |
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SampleType | ThiskitisusedforquantitativedetectionofhumanPLGFincellculturesupernates,serum,plasma(heparin,EDTA,citrate)andurine. |
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Specimen/Volumes | RefertoManual |
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SwissProtNumber | P49763 |
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Concentration | LotSpecific |
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Applications | ELISA |
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GINumber | 5228 |
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StABIlity | Fourmonthsat4Candeightmonthsat-20C. |
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Reactivity | ReactivetoHuman.Thereisnodetectablecross-reactivitywithotherrelevantproteins. |
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KitSize | 1x96wellplate |
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Storage | Storeat4°Cfor6months,at-20°Cfor12months.Avoidmultiplefreeze-thawcycles(Shippedwithwetice.) |
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IntendedUse | ResearchUseOnly |
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